Publications by authors named "A M Lale"
The development of ion-sensitive field-effect transistor (ISFET) sensors based on silicon nanowires (SiNW) has recently seen significant progress, due to their many advantages such as compact size, low cost, robustness and real-time portability. However, little work has been done to predict the performance of SiNW-ISFET sensors. The present study focuses on predicting the performance of the silicon nanowire (SiNW)-based ISFET sensor using four machine learning techniques, namely multilayer perceptron (MLP), nonlinear regression (NLR), support vector regression (SVR) and extra tree regression (ETR).
View Article and Find Full Text PDFRoot angle is a critical factor in optimizing the acquisition of essential resources from different soil depths. The regulation of root angle relies on the auxin-mediated root gravitropism machinery. While the influence of ethylene on auxin levels is known, its specific role in governing root gravitropism and angle remains uncertain, particularly when Arabidopsis (Arabidopsis thaliana) core ethylene signaling mutants show no gravitropic defects.
View Article and Find Full Text PDFArticle Synopsis
- The study explores how polymer inclusion can improve the biopharmaceutical performance of Aprepitant (APT) using a solid dispersion approach with phospholipids, identifying HPMCAS as the most effective polymer through preliminary screening.
- Binary (BD) and ternary (TD) phospholipid dispersions were created and showed significantly higher drug release rates—4.8 times for BD and 9.9 times for TD—compared to crystalline APT, along with reduced food effects during dissolution studies.
- In vitro and in vivo evaluations indicated that both BD and TD offered enhanced drug permeability and absorption, leading to increases in metrics like Cmax and AUC compared to traditional drug suspension, suggesting a promising
We show here brand-new possibilities of lab-in-lab fabrication while combining holographic photopolymerization and microfluidics. One shot real-time 3D-printing can produce 3D architectured microchannels, or free-standing complex micro-objects eventually in flow. The methodology is very versatile and can be applied to , acrylate resins or hydrogels.
View Article and Find Full Text PDFBackground: It aimed to evaluate the relationship between the systemic inflammatory markers and the lymph node metastasis in clinical stages I to II right-sided colon cancers.
Patients And Methods: A total of 51 eligible clinical stages I to II right-side located colon cancer patients were included in the study. Complete mesocolic excision and central vascular ligation procedures were performed in all cases.