Publications by authors named "A M Kocharian"

Nucleus accumbens dopamine signaling is an important neural substrate for decision-making. Dominant theories generally discretize and homogenize decision-making, when it is in fact a continuous process, with evaluation and re-evaluation components that extend beyond simple outcome prediction into consideration of past and future value. Extensive work has examined mesolimbic dopamine in the context of reward prediction error, but major gaps persist in our understanding of how dopamine regulates volitional and self-guided decision-making.

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Background: Reconnection of the mitral isthmus (MI) is common after radiofrequency ablation (RFA). Vein of Marshall ethanol infusion (VOMEI) expedites MI ablation, but long-term results are unclear.

Objectives: This study sought to determine anatomic substrates of failed MI ablation, with and without VOMEI.

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Article Synopsis
  • SARS-CoV-2 Omicron variants may affect how well vaccines work and how long immunity lasts, prompting a study on the effectiveness of the Pfizer-BioNTech vaccine among different age groups in the U.S.
  • From January 16 to May 28, 2022, researchers analyzed COVID-19 infection rates relative to vaccination status across multiple jurisdictions, tracking declines in vaccine effectiveness over time.
  • Results showed lower vaccine protection in younger age groups, particularly those aged 5-11, and a general decline in effectiveness for all ages as time since vaccination increased, indicating a need to monitor waning immunity during the Omicron surge.
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