Publications by authors named "A M Killian"
Purpose: To explore and describe therapeutic approaches for the prevention of upper limb (UL) repetitive strain injuries (RSI) amongst computer users in the twenty-first century.
Methods: A scoping review was conducted using the method described by Arksey and O'Malley, further enhanced by Levac et al. to ensure rigor, validity and reliability during analysis.
The combination of vancomycin and piperacillin-tazobactam (VPT) has been associated with acute kidney injury (AKI) in hospitalized patients when compared to similar combinations. Additional studies examining this nephrotoxic risk in critically ill patients have not consistently demonstrated the aforementioned association. Furthermore, patients with baseline renal dysfunction have been excluded from almost all of these studies, creating a need to examine the risk in this patient population.
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- The guideline aims to create evidence-based recommendations for ICU clinicians treating adults with acute liver failure (ALF) or acute on chronic liver failure (ACLF).
- A panel of 27 experts conducted systematic reviews and categorized their findings into Population, Intervention, Comparison, and Outcomes (PICO) questions to guide clinical practice.
- The resulting 28 recommendations include five strong recommendations and 21 conditional ones, but many are based on low-quality evidence, highlighting areas that need further research.