Publications by authors named "A M Keohane"
Article Synopsis
- Mirikizumab, an anti-interleukin-23 monoclonal antibody, showed efficacy and safety for treating moderately to severely active ulcerative colitis, with an extended treatment option available for non-responders after 12 weeks.
- In the study, 53.7% of patients who initially did not respond achieved a clinical response after additional doses, and by Week 52, over 72% of patients had a clinical response, while 36.1% reached clinical remission.
- Factors influencing success in treatment included being over 40 years old, not having prior biologic therapies, and showing improvement in disease severity by Week 12, with mostly mild side effects reported.
Purpose/objectives: This study aimed to determine how the COVID-19 pandemic and extensive use of personal protective equipment (PPE) have affected the perception of the practice of dentistry in an urban dental school in the USA.
Methods: In 2021, an electronic cross-sectional questionnaire was sent to school faculty via email, while predoctoral, clinical dental students were invited to participate during clinical group meetings. Data were analyzed using descriptive statistics.
Objective: The purpose of this study is to investigate the pathogenic role of PPARα in periodontal antigen treated gingival cells in vitro and in experimental periodontitis in vivo .
Methodology: Gingival fibroblasts, gingival epithelial cells and splenocytes were isolated from C57BL/6J wild type (WT) mice and treated with fixed P. gingivalis at for 48 hours.
Background: There is global momentum to establish scalable Quality Improvement (QI) skills training curricula. We report development of an implementation plan for national scale-up of the 'Education in Quality Improvement' program (EQUIP) in UK urology residencies.
Materials & Methods: Theory-of-Change (ToC) methodology was used, which engaged EQUIP stakeholders in developing a single-page implementation 'Logic Model' in 4 study phases (2 stakeholder workshops (N = 20); 10 stakeholder interviews).