Publications by authors named "A M Joret"
Background: Pain management is an essential and complex issue for non-communicative patients undergoing sedation in the intensive care unit (ICU). The Behavioral Pain Scale (BPS), although not perfect for assessing behavioral pain, is the gold standard based partly on clinical facial expression. , an automatic pain assessment tool based on facial expressions in critically ill patients, is a much-needed innovative medical device.
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- A phase 3 clinical trial investigated if intravenous hydrocortisone could reduce mortality in patients with severe community-acquired pneumonia compared to a placebo.
- The study involved 800 patients, and results showed that those receiving hydrocortisone had a significantly lower death rate (6.2%) at 28 days versus 11.9% in the placebo group.
- Additionally, patients on hydrocortisone required less mechanical ventilation and vasopressors compared to those on placebo, with similar rates of hospital-acquired infections and bleeding risks.
The level of evidence of expert recommendations for starting extracorporeal cardiopulmonary resuscitation (ECPR) in refractory out-of-hospital cardiac arrest (OHCA) and in-hospital cardiac arrest (IHCA) is low. Therefore, we reported our experience in the field to identify factors associated with hospital mortality. We conducted a retrospective cohort study of all consecutive patients treated with ECPR for refractory cardiac arrest without return to spontaneous circulation, regardless of cause, at the Caen University Hospital.
View Article and Find Full Text PDFBackground: Nonintubated chest trauma patients with fractured ribs admitted to the intensive care unit (ICU) are at risk for complications and may require invasive ventilation at some point. Effective pain control is essential. We assessed whether epidural analgesia (EA) in patients with fractured ribs who were not intubated at ICU admission decreased the need for invasive mechanical ventilation (IMV).
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- Nephrotoxic drug prescriptions are prevalent among critically ill patients, with 62% receiving at least one such drug, contributing to acute kidney injury (AKI) occurrences.
- A significant number of patients developed or worsened AKI, revealing a clear association between the nephrotoxic drug burden and AKI incidence, particularly in patients with less severe illness.
- This study suggests that monitoring nephrotoxic burden using a simple drug.day calculation can help clinicians evaluate risk and potentially reduce AKI in intensive care settings.