Publications by authors named "A M Jette"
During embryogenesis, cells arrange into precise patterns that enable tissues and organs to develop specialized functions. Despite its critical importance, the molecular choreography behind these collective cellular behaviors remains elusive, posing a major challenge in developmental biology and limiting advances in regenerative medicine. By using the mouse hair follicle as a mini-organ system to study the formation of bud-like structures during embryonic development, our work uncovers a crucial role for the Rho GTPase regulator ARHGEF3 in hair follicle morphogenesis.
View Article and Find Full Text PDFThe subcellular distribution of the polarity protein Yurt (Yrt) is subjected to a spatio-temporal regulation in Drosophila melanogaster embryonic epithelia. After cellularization, Yrt binds to the lateral membrane of ectodermal cells and maintains this localization throughout embryogenesis. During terminal differentiation of the epidermis, Yrt accumulates at septate junctions and is also recruited to the apical domain.
View Article and Find Full Text PDFArticle Synopsis
- Research in health policy, systems, and services (HPSSR) has gained traction in rehabilitation, driven by the need to tackle complex healthcare challenges effectively.
- The World Health Assembly's resolution emphasizes promoting high-quality rehabilitation research and outlines various HPSSR study designs at macro, meso, and micro levels.
- The paper categorizes research questions, provides examples of methodologies, and highlights the importance of implementing findings in clinical practice to improve healthcare delivery and patient outcomes.