Determining Antiradical Capacity of Medicinal Plant Extract Individual Constituents Using Post-Column Reaction Method.

The post-column reaction method enables the evaluation of the antiradical capacity of individual components in a mixture by separating the components using HPLC and measuring stable free radical (e.g., DPPH●) scavenging that occurs after the chromatography column.

ChromGene: gene-based modeling of epigenomic data.

Various computational approaches have been developed to annotate epigenomes on a per-position basis by modeling combinatorial and spatial patterns within epigenomic data. However, such annotations are less suitable for gene-based analyses. We present ChromGene, a method based on a mixture of learned hidden Markov models, to annotate genes based on multiple epigenomic maps across the gene body and flanks.

The impact of agency on time and risk preferences.

Scholars have long argued for the central role of agency-the size of one's choice set-in the human experience. We demonstrate the importance of agency in shaping people's preferences. We first examine the effects of resource scarcity-which has been associated with both impatience and a lack of agency-on patience and risk tolerance, successfully replicating the decrease in patience among those exposed to scarcity.

An integrative approach for fine-mapping chromatin interactions.

Motivation: Chromatin interactions play an important role in genome architecture and gene regulation. The Hi-C assay generates such interactions maps genome-wide, but at relatively low resolutions (e.g.

Genome and methylome of the oleaginous diatom reveal genetic flexibility toward a high lipid phenotype.

Background: Improvement in the performance of eukaryotic microalgae for biofuel and bioproduct production is largely dependent on characterization of metabolic mechanisms within the cell. The marine diatom which was originally identified in the Aquatic Species Program, is a promising strain of microalgae for large-scale production of biofuel and bioproducts, such as omega-3 fatty acids.

Results: We sequenced the nuclear genome and methylome of this oleaginous diatom to identify the genetic traits that enable substantial accumulation of triacylglycerol.