Publications by authors named "A M J van der Kley"
Article Synopsis
- Parasitic infections in the U.S. primarily affect immigrants and travelers, often leading to delayed diagnoses by physicians unfamiliar with these diseases.
- Nearly 2,000 cases of imported malaria occur annually, with severe symptoms that can mimic bacterial sepsis, and treatment requires careful management to improve survival.
- Strongyloidiasis, endemic in warm regions, can stay dormant for years and worsen if corticosteroids are used, while other infections like cystic echinococcosis and paragonimus present with specific respiratory symptoms and are found in various global regions, including parts of North America.
Tissue-resident memory T (T ) cells play a central role in immune responses to pathogens across all barrier tissues after infection. However, the underlying mechanisms that drive T differentiation and priming for their recall effector function remains unclear. In this study, we leveraged both newly generated and publicly available single-cell RNA-sequencing (scRNAseq) data generated across 10 developmental time points to define features of CD8 T across both skin and small-intestine intraepithelial lymphocytes (siIEL).
View Article and Find Full Text PDFEssential oils have been proposed as alternatives to antibiotic use in food animal production. This study evaluated 3 chemotypes of the Origanum genus, containing varying amounts of secondary metabolites carvacrol, thymol, and sabinene, in the broiler chicken diet. Aerial parts of Origanum vulgare L.
View Article and Find Full Text PDFA 14-years-old Dutch boy had pain in both calves, recurrent oral ulcers, fever, hoarseness and erythema nodosum-like skin lesions. Laryngoscopic examination revealed a vocal cord ulcer and leukocytoclastic vasculitis was visible in a skin biopsy. Based on the clinical picture, the diagnosis of 'incomplete juvenile Behçet's disease' was established.
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