Publications by authors named "A M J MacLullich"
Article Synopsis
- Delirium can lead to long-term brain problems, and the study looked at specific brain markers related to both delirium and dementia.
- Researchers studied 35 people with ongoing delirium and compared them to 20 people with dementia to see how their brain markers were different.
- The findings showed that certain brain markers were higher in people with persistent delirium, suggesting that this condition affects the brain in specific ways even if someone has dementia too.
Background: Delirium is a serious neuropsychiatric syndrome with adverse outcomes, which is common but often undiagnosed in terminally ill people. The 4 'A's test or 4AT (www.the4AT.
View Article and Find Full Text PDFIntroduction: The aims of this systematic review and meta-analysis were to determine if after hip fracture surgery (1) early mobilisation is associated with improved clinical outcomes, and if so (2) are benefits directly proportional to how soon after surgery the patient mobilises.
Methods: A Preferred Reporting Items for Systematic Reviews and Meta-Analyses systematic review was conducted using four databases to identify all studies that compared postoperative early mobilisation with delayed mobilisation, in patients after hip fracture surgery. The Critical Appraisal Skills Programme checklist was employed for critical appraisal and evaluation of all studies that met the inclusion criteria.
Delirium is common in hospitalised patients, and there is currently no specific treatment. Identifying and treating underlying somatic causes of delirium is the first priority once delirium is diagnosed. Several international guidelines provide clinicians with an evidence-based approach to screening, diagnosis and symptomatic treatment.
View Article and Find Full Text PDFBackground: Multiple short delirium detection tools have been validated in research studies and implemented in routine care, but there has been little study of these tools in real-world conditions. This systematic review synthesized literature reporting completion rates and/or delirium positive score rates of detection tools in large clinical populations in general hospital settings.
Methods: PROSPERO (CRD42022385166).