Publications by authors named "A M Imbert"
A study of the lipidome and proteome was performed on milk fat globule membranes (MFGM) originating from milk samples from high (HL) and low (LL) lipolysis groups of cows. Combined univariate and multivariate statistical analyses proposed a set of variables highly associated to contrasted samples with regard to milk lipolysis. Milk from HL group were related to 4 phosphatidylinositols, 8 phosphatidylcholines, 1 sphingomyelin and 27 proteins, among them the phosphatidylcholine/phosphatidylethanolamine ratio and ORM1 may contribute to the membrane remodeling of the MFGM.
View Article and Find Full Text PDFObjectives: Prone positioning (PP) has benefits in patients with acute respiratory distress syndrome. The objective of this study was to compare the effects and complications of PP in obese versus non-obese patients with moderate-to-severe acute respiratory distress syndrome after cardiothoracic surgery.
Methods: We retrospectively analysed a database established in 2014-2021 in an intensive care unit.
Article Synopsis
- Relapse after stopping immunosuppression treatment is common in Autoimmune Hepatitis (AIH) patients, and there's a need for better non-invasive biomarkers to predict this risk.
- The study analyzed blood samples from 58 active AIH patients, 56 in remission, and 31 with NASH, focusing on the levels of activated T cell subsets and the cytokine BAFF.
- Results showed that increased frequencies of certain activated T cells and high BAFF levels in remission patients were strongly linked to a higher chance of relapse after treatment withdrawal, suggesting these could serve as useful biomarkers for monitoring AIH.
Article Synopsis
- Understanding RNA targeting to membraneless organelles like P-bodies (PBs) is crucial for revealing their functions in cells.
- This study shows that PBs in HEK293 cells undergo significant changes in RNA content throughout the cell cycle, with different mRNA localization patterns appearing at various stages (G1, S, G2).
- The findings suggest that PBs actively sort mRNAs based on their translation status and characteristics, implying that they play a more dynamic role than merely housing excess untranslated mRNAs.
Probabilistic Prediction of Gastrointestinal Ischemia after Cardiothoracic Surgery.
Thorac Cardiovasc Surg
October 2024
Background: Gastrointestinal ischemia (GIisch) is challenging to diagnose in patients after cardiothoracic surgery. Computed tomography angiography (CTA) carries substantial false-negative and false-positive rates. The aim of the study was to evaluate if a combination of readily available variables improves the diagnosis of GIisch after cardiothoracic surgery.
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