Objective: The aim of this study was to design and use a headache diary in patients with frequent tension-type headaches (TTH). Another aim was to assess the relationship among oral behaviors, range of motion, and tenderness to palpation of the craniomandibular muscles.
Methods: Thirty-four patients participated in this prospective observational study for a 3-month period at the Adavall Clinic for Physiotherapy and Rehabilitation (Valladolid, Spain) in 2019.
Herein, we report the design, synthesis, and characterisation of a new library of enantiopure aminoalcohol fluorenes, as well as their in vitro evaluation for biological properties, including activity against two strains of P. falciparum (3D7 and W2) and cytotoxicity on the HepG2 cell line. All tested compounds exhibited good to excellent antimalarial potency with IC values ranging from 0.
View Article and Find Full Text PDFCyanobacteria developed oxygenic photosynthesis and represent the phylogenetic ancestors of chloroplasts. The model strain Anabaena sp. strain PCC 7120 grows as filaments of communicating cells and can form heterocysts, cells specialized for N fixation.
View Article and Find Full Text PDFSystemic lupus erythematosus (SLE) is an autoimmune disorder characterized by a wide variety of symptoms, including frequent neurological and psychiatric symptomatology. Psychiatric symptoms encountered in SLE are frequent, between 37 and 95% of SLE patients present them, can appear at any point in the course of the disease and may include almost any type of disorder. We present the case of a 32-year-old woman who presented an SLE debut with catatonic symptoms without previous psychiatric history, representing a diagnostic and therapeutic challenge given that the diagnosis was initially wrongly filtered out and required up to three hospital admissions in a row to reach a proper diagnosis and treatment.
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