Dissemination of extensively drug-resistant NDM-producing in Europe linked to patients transferred from Ukraine, March 2022 to March 2023.

BackgroundThe war in Ukraine led to migration of Ukrainian people. Early 2022, several European national surveillance systems detected multidrug-resistant (MDR) bacteria related to Ukrainian patients.AimTo investigate the genomic epidemiology of New Delhi metallo-β-lactamase (NDM)-producing from Ukrainian patients among European countries.

Surveillance of vancomycin-resistant enterococci reveals shift in dominating clusters from to clusters, Denmark, 2015 to 2022.

BackgroundVancomycin-resistant enterococci (VRE) are increasing in Denmark and Europe. Linezolid and vancomycin-resistant enterococci (LVRE) are of concern, as treatment options are limited. Vancomycin-variable enterococci (VVE) harbour the gene complex but are phenotypically vancomycin-susceptible.

Co-occurrence of triple carbapenemase genes, , , and in clinical isolates -first report from Croatia.

Two isolates harbouring three carbapenemase genes each, were isolated from two patients from different ICUs at University Hospital Centre Zagreb, Croatia, which is to our knowledge, the first report of triple carbapenemase (, , and co-existence in strains and also among Enterobacterales members in Croatia. Antimicrobial susceptibility testing showed susceptibility only to colistin and amikacin. The production of carbapenemases was phenotypically tested by immunochromatographic assay and confirmed by PCR.

VirulenceFinder for and : an enhanced database for detection of putative virulence markers by using whole-genome sequencing data.

() is a leading cause of hospital-associated (HA) infections, often enriched in putative virulence markers (PVMs). Recently, the clade B was assigned as (), which usually lack HA- infection markers. Available databases for extracting PVM are incomplete and/or present an intermix of genes from and , with distinct virulence profiles.