[Lymphogranuloma venerum as ulcerous proctitis in men who have sex with men].

Lymphogranuloma venerum (LGV), previously lymphogranulma inguinale, is a sexually transmitted infection caused by Chlamydia trachomatis serovar L1-L3. The disease is primarily manifested by a small papule or erosion in the genital region, followed by lymphadenitis and development of abscesses. Proctitis and systemic disease may occur subsequently.

An outbreak of syphilis in Oslo.

During 1999 and 2000, an outbreak of syphilis occurred in Norway: 93 cases were reported to the National Institute of Public Health. This report summarizes a retrospective investigation of the medical records of 60 patients with primary, secondary and early latent syphilis treated during 1999-2000 at the Department of STD at the Ullevål University Hospital in Oslo. Five women and 55 men were treated, mean age 38.

A double blind study of single dose azithromycin and doxycycline in the treatment of chlamydial urethritis in males.

Objective: To compare the efficacy and safety of azithromycin and doxycycline in the treatment of males with uncomplicated urethritis caused by chlamydia trachomatis.

Design: A multicentre, double-blind, randomised treatment study.

Subjects: 130 male outpatients with clinical signs and symptoms of urethritis.

Genital human papilloma virus infection in Oslo studied by dot blot DNA hybridization and the polymerase chain reaction.

Samples from patients with genital condyloma acuminata or with cervical condylomas and/or dysplasia and from women without cytological/clinical evidence of cervical affection were examined by dot blot DNA hybridization or the polymerase chain reaction (PCR). The PCR was much more sensitive than dot blot, more than doubling the human papilloma virus (HPV) findings. HPV DNA, mainly HPV 6/11, was detected in 18 of 19 biopsies of condyloma acuminata, whereas HPV 16 was most frequently detected in the 21 cervices (76%) with condyloma and/or dysplasia.

[Acyclovir creme in recurrent herpes genitalis].

A multicenter clinical, double-blind crossover trial was conducted in 65 men and 31 women experiencing recurrent episodes of genital herpes in order to compare the effect of acyclovir in propylenglycol (40% cream) with that of cream alone (placebo). 59.4 of the patients on acyclovir experienced a beneficial effect in relation to the usual clinical course of their herpetic eruptions.