Youth participatory action research (YPAR) to promote educational equity.

The article uses theory and qualitative evidence to show how youth participatory action research (YPAR) can advance educational equity. YPAR engages young people and adult allies in research and action on issues in their schools and communities. Interviews with over two dozen YPAR researchers-students and partner teachers-elaborate the mechanisms through which school-based YPAR can affect equity, including through direct changes to policy and practice as a result of YPAR actions, a school culture that values student experiences, transformative teacher-student relationships, and improved individual outcomes for participants.

Genomic ascertainment to quantify prevalence and cancer risk in adults with pathogenic and likely pathogenic germline variants in RASopathy genes.

Purpose: Genomic ascertainment of electronic health record-linked exome data in two large biobanks was used to quantify germline pathogenic/likely pathogenic (P/LP) variant prevalence, cancer prevalence, and survival in adults with non- RAS/mitogen-activated protein kinase genes (RASopathies).

Patients And Methods: Germline RASopathy variants were examined from adult participants in UK Biobank (UKBB; n=469,802), Geisinger MyCode (n=167,050) and Mount Sinai Bio (n=30,470). Variants were classified as per American College of Medical Genetics/Association for Molecular Pathology criteria and reviewed by a RASopathy variant expert.

Gallstone Ileus as an Occult Cause of Small Bowel Obstruction and Subsequent Large Bowel Obstruction: A Report of a Rare Case.

Gallstone ileus, a rare cause of mechanical bowel obstruction, occurs due to the formation of a cholecystenteric fistula allowing gallstones to migrate into the gastrointestinal tract. The condition occurs mostly in elderly patients, particularly women, and carries a significant mortality risk due to delayed diagnosis. This case report discusses a 77-year-old female patient with a history of chronic medical conditions, who self-presented with periumbilical pain, nausea, and reduced bowel movements.

Performance and usability evaluation of three LDH-based malaria rapid diagnostic tests in Kédougou, Senegal.

Background: The emergence of -deleted parasites threatens histidine-rich protein 2 (HRP2)-based malaria rapid diagnostic test (RDT) performance. RDTs targeting () lactate dehydrogenase (LDH) may address current product limitations and improve case management.

Objectives: To evaluate the performance and usability of three LDH-based RDTs in febrile patients.