Publications by authors named "A M Genkin"
Keratinocytes are an essential component of the epidermis that undergoes constant proliferation and differentiation. However, the dysregulation of keratinocyte differentiation has been implicated in various skin disorders such as psoriasis. Imiquimod, otherwise known as IMQ, is a topical immunomodulator often used to induce psoriasis-like lesions in murine models for research purposes.
View Article and Find Full Text PDFArticle Synopsis
- Researchers are developing a normative theory to better understand neuronal function by modeling neurons as optimal feedback controllers rather than just predictive entities.
- This approach allows neurons to interact with their environment, including other neurons and external feedback, enabling them to adjust their output toward achieving specific desired states.
- The new model, based on direct data-driven control, explains various neurophysiological phenomena and moves away from traditional neuron models, presenting a more biologically realistic framework for constructing neural networks.
Computing sparse redundant representations is an important problem in both applied mathematics and neuroscience. In many applications, this problem must be solved in an energy-efficient way. Here, we propose a hybrid distributed algorithm (HDA), which solves this problem on a network of simple nodes communicating by low-bandwidth channels.
View Article and Find Full Text PDFThe informational technology designed for systems analysis of changes in the characteristics of single variations in physiological process is outlined. This technology has been used in the module of analysis of the physiological processes of an software complex.
View Article and Find Full Text PDFAim: To determine mechanisms inducing changes in lung gas exchange after berotec inhalation in patients with bronchial asthma (BA).
Materials And Methods: A study was made of external respiration function including estimation of lung transfer factor (TLCO sbh.) and its components--transfer coefficient (KCO), membrane diffusion capacity (DM), pulmonary capillary blood volume (Vc)--by the single breath holding method on CO in 14 healthy persons and 39 patients with BA before and after berotec inhalation.