Publications by authors named "A M Gargiulo"

Background: C3 glomerulopathy is a rare clinical entity characterized by dysregulation of the alternative complement pathway in glomerular disease. Studies defining the natural history of C3G in the pediatric population are scarce.

Methods: Patients included in this retrospective study were diagnosed between 2011 and 2020 in 12 European pediatric nephrology units.

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  • Fibroids are non-cancerous growths in the uterus that can negatively affect quality of life, prompting the need for personalized treatment options and better communication tools for shared decision-making among patients and healthcare providers.* -
  • A user-centered approach was used to develop two conversation aids—one text-based and one picture-enhanced—through stakeholder focus groups and user-testing interviews, with efforts made to translate them into Spanish simultaneously.* -
  • Initial feedback from focus groups and user-testing showed the conversation aids were well-received, but ongoing implementation revealed the need for significant updates to reflect new treatment information and accommodate stakeholder suggestions.*
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  • The study explored childhood environments and stress-coping strategies in three patient groups: those with functional dissociative seizures (FDS), drug-resistant epilepsy without psychiatric issues (DREnc), and drug-resistant epilepsy with psychiatric issues (DREpc).
  • Results indicated that negative maternal responses were linked to higher FDS probabilities, while chaotic family environments increased the likelihood of psychiatric comorbidity in DRE patients. Additionally, DREpc and FDS patients used different coping strategies compared to DREnc, who mainly focused on problem-solving.
  • The findings suggest that invalidating environments can predict FDS and psychiatric disorders in epilepsy, highlighting the need for psychotherapeutic interventions that address these social and psychological
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Introduction: The clinical evolution of steroid-sensitive forms of pediatric idiopathic nephrotic syndrome (INS) is highly heterogeneous following the standard treatment with prednisone. To date, no prognostic marker has been identified to predict the severity of the disease course starting from the first episode.

Methods: In this monocentric prospective cohort study we set up a reproducible and standardized flow cytometry panel using two sample tubes (one for B-cell and one for T-cell subsets) to extensively characterized the lymphocyte repertoire of INS pediatric patients.

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Introduction: Parastomal hernia (PSH) is the most common and challenging complication after stoma creation, with an estimated 50% incidence 2 years after the index surgery. Mesh repair is the treatment of choice. Laparoscopic and/or robotic approaches allow acceptable outcomes.

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