Publications by authors named "A M GRAFF"

The increasing availability of cross-linguistic databases dedicated to documenting morphosyntactic, lexical and phonological features has proliferated the use of such data for studies on language evolution and human history. However, most of these databases were not designed to ensure independence of features, such that it is not valid to jointly use all their features in large-scale statistical analyses assuming independence of inputs. Here, we curate published data from five large linguistic databases to generate two global-scale cross-linguistic datasets: GBI (from the Grambank dataset), and TLI (using inputs from the World Atlas of Language Structures, AUTOTYP, PHOIBLE and Lexibank).

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In the search for iron, an essential element in many biochemical processes, microorganisms biosynthesise dedicated chelators, known as siderophores, to sequester iron from their environment and actively transport the siderophore complex into the cell. This process has been implicated in bacterial pathogenesis and exploited through siderophore-antibiotic conjugates as a method for selective antibiotic delivery. Here we review this Trojan-horse approach including design considerations and potential in diagnostics and infection imaging.

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Exposure to stress is known to affect biological aging as well as individuals' susceptibility to a wide variety of mental illnesses, such as schizophrenia. There is an established relationship between the onset of schizophrenia spectrum disorders (SSD) and biological aging. On the other hand, epigenetic modifications, such as DNA methylation (DNAm), are used as biomarkers for biological aging and were previously proven to be altered in schizophrenia.

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