Publications by authors named "A M Farahat"

Statement Of Problem: Duplicating complete dentures and achieving accurately fitting prostheses poses a challenge. Conventional methods are often time-consuming and susceptible to human error. Advancements in digital technology for denture fabrication offer a promising alternative to conventional duplication techniques, but studies comparing the methods are lacking.

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Breast plasmacytoma is an uncommon extramedullary manifestation of multiple myeloma (MM). This case presents a primary extramedullary plasmacytoma and progression to MM with breast involvement after 12 years of discovering the disease. The patient is a 54-year-old woman who initially presented with a right humerus pathological fracture that turned out to be a primary extramedullary plasmacytoma.

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Article Synopsis
  • This study investigates metronidazole resistance and virulence genotypes in H. pylori from Egyptian patients, highlighting the public health issue of antibiotic resistance in this bacterium.
  • The research involved collecting gastric biopsies from 250 symptomatic patients and using molecular techniques to analyze antibiotic resistance mutations and virulence factors.
  • Findings showed that 43.6% of H. pylori isolates were resistant to metronidazole, with significant links between resistance and virulence genes, suggesting that genetic factors may contribute to how the bacteria resist treatment.
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The recognition of specific genomic arrangements by rationally designed small molecules is fundamental for the expansion of targeted gene expression. Here, we report the first X-ray crystal structures that demonstrate single G (guanine) recognition by a highly selective diamidine (DB2447) in a mixed DNA sequence. The study presents detailed structural information on the mechanism of single G recognition by D2447 and its various interactions in the DNA minor groove.

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