Statement Of Problem: Duplicating complete dentures and achieving accurately fitting prostheses poses a challenge. Conventional methods are often time-consuming and susceptible to human error. Advancements in digital technology for denture fabrication offer a promising alternative to conventional duplication techniques, but studies comparing the methods are lacking.
View Article and Find Full Text PDFBreast plasmacytoma is an uncommon extramedullary manifestation of multiple myeloma (MM). This case presents a primary extramedullary plasmacytoma and progression to MM with breast involvement after 12 years of discovering the disease. The patient is a 54-year-old woman who initially presented with a right humerus pathological fracture that turned out to be a primary extramedullary plasmacytoma.
View Article and Find Full Text PDFJ Infect Chemother
October 2024
The recognition of specific genomic arrangements by rationally designed small molecules is fundamental for the expansion of targeted gene expression. Here, we report the first X-ray crystal structures that demonstrate single G (guanine) recognition by a highly selective diamidine (DB2447) in a mixed DNA sequence. The study presents detailed structural information on the mechanism of single G recognition by D2447 and its various interactions in the DNA minor groove.
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