Publications by authors named "A M Evsikov"
Article Synopsis
- Schwannomas are benign nerve sheath tumors that generally grow slowly and are often asymptomatic, with surgical removal only needed for symptomatic cases.
- They account for about 7% of primary tumors in the central nervous system, with rare occurrences originating from the thyroid gland, potentially confusing them with thyroid or parathyroid tumors.
- Diagnosis of thyroid tumors typically involves fine-needle aspiration biopsies, but challenges arise when results are inconclusive, highlighting the need for thorough evaluation, as seen in a case study of a patient diagnosed with a neck schwannoma.
Adrenal gland incidentaloma (incidental - sudden, accidental) is a mass of the adrenal gland(s), accidentally detected by an instru-mental examination conducted for other reasons. The frequency of detection of this pathology based on computer tomography of the abdominal organs is 0.5%-2%.
View Article and Find Full Text PDFAnaplastic thyroid carcinoma is a high-grade aggressive tumor with a tendency for early metastasis. The paper describes a rare case of Stage IVB anaplastic thyroid carcinoma, including its clinical, instrumental, morphological, and autopsy findings, in a 66-year-old woman.
View Article and Find Full Text PDFIn mammalian ovarian follicles, follicle stimulating hormone (FSH) and luteinizing hormone (LH) signal primarily through the G-protein Gs to elevate cAMP, but both of these hormones can also elevate Ca2+ under some conditions. Here, we investigate FSH- and LH-induced Ca2+ signaling in intact follicles of mice expressing genetically encoded Ca2+ sensors, Twitch-2B and GCaMP6s. At a physiological concentration (1 nM), FSH elevates Ca2+ within the granulosa cells of preantral and antral follicles.
View Article and Find Full Text PDFAs one of the most widespread metabolic diseases, atherosclerosis affects nearly everyone as they age; arteries gradually narrow from plaque accumulation over time reducing oxygenated blood flow to central and periphery causing heart disease, stroke, kidney problems, and even pulmonary disease. Personalized medicine promises to bring treatments based on individual genome sequencing that precisely target the molecular pathways underlying atherosclerosis and its symptoms, but to date only a few genotypes have been identified. A promising alternative to this genetic approach is the identification of pathways altered in atherosclerosis by transcriptome analysis of atherosclerotic tissues to target specific aspects of disease.
View Article and Find Full Text PDF