Publications by authors named "A M Espinosa-Garcia"
Objectives: Wastewater-based surveillance applied to SARS-CoV-2 viral load quantification for COVID-19 has become one of the most relevant complementary tools in epidemiologic prevention programs worldwide. However, this valuable decision-making tool still requires fine-tuning to produce comparable results between laboratories, especially when applied to the surveillance of megacities.
Methods: Six laboratories across Mexico and one from the United States executed an interlaboratory study to set up a singular standardized protocol considering method cost, installed infrastructure, materials available, and supply availability for SARS-CoV-2 quantification from five Mexico City sampling sites across this megacity.
Liver cirrhosis causes include alcoholism, viral infections (hepatitis B virus (HBV) and hepatitis C virus (HCV)), alcohol-associated liver disease (ALD), and metabolic dysfunction associated with steatotic liver disease (MASLD), among others. Cirrhosis frequency has increased in recent years, with a prevalence of 1395 cases per 100,000 and a mortality rate of 18 per 100,000, which corresponded to 1,472,000 deaths during 2017. In Mexico, liver disease is a public health problem since it was associated to 41,890 deaths in 2022, including liver cirrhosis (>25,000) and ALD (14,927).
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- Childhood Sexual Abuse (CSA) is linked to a higher likelihood of sexual dysfunction, especially in women compared to men.
- A study involving 426 participants examined sexual dysfunctions in individuals with a history of CSA and addiction issues, using questionnaires and statistical tests for analysis.
- Significant differences were found in multiple areas of sexual dysfunction, indicating that individuals with a history of CSA are more prone to issues like dissatisfaction, vaginismus, and anorgasmia compared to those without such trauma.
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- Aquatic habitats can facilitate the spread of avian influenza virus (AIV) between wild and domestic birds, but the virus's stability in different water sources is not well understood.
- A study in Central Mexico used a multi-criteria decision analysis (MCDA) to evaluate AIV transmission risk, finding that January conditions in the Atarasquillo wetland and many backyard poultry farms pose a higher risk for virus persistence and transmission.
- Key factors that contribute to this risk include water access for poultry and the location of farms near water bodies, emphasizing the need for effective monitoring and intervention strategies to manage AIV spread.
Epstein‑Barr virus (EBV) is an oncovirus associated with various neoplasms, including breast cancer (BC). EBV‑associated oncogenesis requires the action of several viral molecules, such as EBV nuclear antigen 3C, latent membrane protein 1, microRNAs and long non‑coding RNAs, which are able of manipulating the cellular machinery, inducing an evasion of the immune system, blocking apoptosis processes, promoting cell survival and metastasis. The risk of developing cancer is associated with epigenetic alterations and alterations in various signaling pathways.
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