Publications by authors named "A M Engelbrecht"
Background: Neonatal sepsis is a leading cause of death in low- and middle- income countries (LMIC). Increasing antibiotic resistance in early onset (< 72 h of life) bloodstream infection (EO-BSI) pathogens in LMIC has reduced the effectiveness of the recommended empiric antibiotic regimen (ampicillin plus gentamicin).
Methods: We retrospectively analysed blood culture-confirmed EO-BSI episodes at nine neonatal units from three central and six peripheral hospitals in the Western Cape Province, South Africa between 1 January 2017 and 31 December 2018.
1. The heritability (h) of liveweight (LW) in ostriches can be highly variable, depending on age at recording. The objective of this study was to consider random regression (RR) as an alternative to the multi-trait (MT) structure for the analysis of repeated measures of LW.
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- The genus Bullacris, previously revised in 1965, requires an update due to new findings and the need for a male description of the species B. boschimana, based on morphological and acoustic evidence.
- This study utilized measurements from type specimens and museum collections, alongside acoustic signal analysis, to compare species and investigate genetic relationships through mitochondrial and nuclear DNA.
- Notable findings showed similarities among certain species (B. discolor with B. serrata, and B. intermedia with B. membracioides), suggesting possible spatial separation while highlighting the need for further geographic sampling to clarify their relationships.
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- * The study involved 23,748 neonates and found a HA-BSI rate of 2.0 per 1000 patient days, with the highest rates in very low birth weight infants and high mortality (31.8%) associated with infections, particularly in preterm and those with Gram-negative/fungal infections.
- * Empiric antibiotic coverage varied by hospital, averaging 66-92%, but concerns were raised about increasing carbapenem resistance, highlighting the need for regular updates to treatment protocols.
Cervical cancer poses a significant global health challenge, particularly impacting women in economically developing nations. This disparity stems from a combination of factors, including inadequate screening infrastructure and resource limitations. However, the foremost contributor is the widespread lack of awareness and limited accessibility to Human Papillomavirus (HPV) vaccination, which is a key preventative measure against cervical cancer development.
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