Expression of cytokines, chemokines, and chemokine receptors in oral ulcers of patients with Behcet's disease (BD) and recurrent aphthous stomatitis is Th1-associated, although Th2-association is also observed in patients with BD.

Objective: Although the pathogenesis of Behcet's disease (BD) is unknown, immune dysfunction appears to be involved. To improve understanding of the role of T cells and cytokines in BD, the current study analysed the localization and extent of expression of T cell subsets, cytokines, chemokines, and chemokine receptors in oral ulcers from BD patients and for comparison in oral ulcers from patients with recurrent aphthous stomatitis (RAS), as well as in healthy oral mucosa.

Methods: Biopsies from oral ulcers of 25 BD patients and 19 RAS patients and oral mucosa from six healthy volunteers were immunoperoxidase stained.

Cemento-ossifying fibroma occurring in an elderly patient. A case report and a review of literature.

Cemento-ossifying fibromas (COF) are benign lesions affecting the jaws and other craniofacial bones. They commonly affect adults between the third and fourth decade of life. Radiographically, they appear as well-defined unilocular or multilocular intraosseous masses, commonly in the premolar/molar region of the mandible.

Massive maxillary radicular cyst presenting as facial fracture and abscess, a case report.

Radicular cysts arise from non-vital teeth. They are inflammatory in nature and are the most common cystic lesion found in the jaw. We present a case of a massive maxillary radicular cyst in a 20 year-old man, diagnosed following an alleged assault and facial fracture.

Expression of adhesion and activation molecules in human buccal epithelial cell lines and normal human buccal epithelium in situ.

An in vitro culture system may be used to analyse interactions between T cells and epithelium. We have analysed two human buccal squamous epithelial cell lines: SqCC/Y1, derived from a buccal carcinoma, and SVpgC2a, an SV-transformed healthy buccal squamous epithelium. Under serum-free culture conditions, the cell lines resemble normal buccal squamous epithelium in situ in their expression of MHC class I, CD29 (beta1 integrin), CD40, CD44, CD54 (ICAM-1), CD58 (LFA-3), CD95 (Fas), and E-cadherin.