Publications by authors named "A M Cuvelier"
Background: The ventilatory physiopathology of patients with interstitial lung disease (ILD) remains poorly understood. We aimed to personalize a mechanical simulator to model healthy and ILD profiles ventilation, and to evaluate the effect of spontaneous breathing on respiratory mechanics at rest and during exercise.
Methods: In a 2-compartment lung simulator (ASL 5000), we modeled 1 healthy and 3 ILD profiles, at rest and during exercise, based on physiological data from literature and patients.
Article Synopsis
- A comparison study was conducted to evaluate the technical performance of various ventilators designed for non-invasive ventilation (NIV) in respiratory and intensive care units (ICU).
- The study tested five ICU ventilators, two dedicated NIV ventilators, and one transport ventilator under different simulated conditions including lung profiles, air leakage levels, and pressure settings.
- Results showed that ICU ventilators had a significantly higher Asynchrony Index (AI) indicating less efficiency compared to dedicated NIV ventilators, especially under normal and restrictive lung conditions, suggesting that dedicated devices may be more effective for NIV.
Article Synopsis
- In a study on chronic respiratory failure patients using home non-invasive ventilation (NIV), researchers investigated the prevalence and impact of side effects caused by masks, finding that 47% of patients experienced moderate to severe issues.
- The research indicated that patients with oronasal masks reported more severe side effects compared to those using nasal masks, which were also found to be more stable in a bench study.
- The findings suggest that mask-related issues can negatively affect patients' daytime carbon dioxide levels, sleep quality, and overall quality of life, recommending nasal masks as a preferable option.
Introduction: Novel biomarkers of hypoxic load have emerged, as sleep apnea-specific hypoxic burden which provides more precise assessment of intermittent hypoxemia severity. Our main objective was to assess the potential benefit of hypoxic burden to identify obesity-related sleep hypoventilation. We hypothesized that hypoxic burden may help diagnose obesity-related sleep hypoventilation better than usual sleep respiratory measures (i.
View Article and Find Full Text PDF[High-flow nasal oxygen therapy and hypercapnic acute respiratory failure].
Rev Mal Respir
September 2024
Humidified high-flow nasal oxygen therapy (HFNO) has, in recent years, come to assume a key role in the management of hypoxemic acute respiratory failure (ARF). While non-invasive ventilation (NIV) currently represents the first-line ventilatory strategy in patients exhibiting hypercapnic ARF, the operating principles and physiological effects of HFNO could be interesting and useful in the initial management of hypercapnic ARF and/or after extubation, particularly in acute exacerbations of chronic obstructive pulmonary disease. Under these conditions, HFNO could be used either alone continuously or in combination with NIV during breaks in spontaneous breathing, depending on the severity and etiology of the underlying hypercapnic ARF.
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