Publications by authors named "A M Clerici"
Article Synopsis
- Cardiac hemangioma is a rare, benign tumor that can be asymptomatic or cause symptoms depending on its location and interaction with nearby structures.
- A case study describes a 79-year-old patient diagnosed with right cardiac hemangioma after experiencing severe symptoms like fluid buildup and heart failure.
- The tumor was successfully removed using cardiopulmonary bypass, leading to a favorable outcome after 12 months, highlighting its unusual size and location near the tricuspid valve.
Impact of 2021 European Academy of Neurology/Peripheral Nerve Society diagnostic criteria on diagnosis and therapy of chronic inflammatory demyelinating polyradiculoneuropathy variants.
Alberto De Lorenzo Giuseppe Liberatore Pietro Emiliano Doneddu Fiore Manganelli Dario Cocito Angelo Maurizio Clerici
Eur J Neurol
April 2024
Article Synopsis
- The 2021 EAN/PNS guidelines provide detailed clinical criteria to diagnose various variants of chronic inflammatory demyelinating polyradiculoneuropathy (CIDP), despite the lack of research on their treatment impact.
- In a study involving 369 patients from the Italian CIDP database, 66% were diagnosed with different CIDP variants using these new criteria, revealing a distribution of typical and atypical forms.
- The findings indicate that patients with multifocal, distal, and sensory CIDP often experience milder symptoms and may respond differently to steroid treatments compared to those with other variants, underscoring the need for specific guidelines in managing CIDP.
Background: To assess the ability of the 2021 European Academy of Neurology/Peripheral Nerve Society (EAN/PNS) clinical criteria for chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) to include within their classification the whole spectrum of clinical heterogeneity of the disease and to define the clinical characteristics of the unclassifiable clinical forms.
Methods: The 2021 EAN/PNS clinical criteria for CIDP were applied to 329 patients fulfilling the electrodiagnostic (and in some cases also the supportive) criteria for the diagnosis of CIDP. Clinical characteristics were reviewed for each patient not strictly fulfilling the clinical criteria ('unclassifiable').
Article Synopsis
- The study examined 276 Italian patients with chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) for the presence of anti-nerve autoantibodies and correlated findings with clinical data.
- Anti-neurofascin155 (NF155) and anti-contactin1 (CNTN1) antibodies were found in a small percentage of patients, with specific clinical symptoms linked to each type of antibody.
- The presence of these antibodies suggests that CIDP may have various underlying mechanisms, leading to different clinical manifestations in patients.