Publications by authors named "A M Chilosi"
Article Synopsis
- Childhood apraxia of speech (CAS) is a genetic speech disorder, and recent advancements in whole exome and genome sequencing have improved the identification of gene variants linked to it, particularly in a new Italian study.
- In a study of 69 Italian children with CAS, researchers used whole exome sequencing to find high-confidence and low-confidence gene variants, revealing new potential genetic links to the disorder.
- The study indicated that many of the identified high-confidence genes are involved in brain regions related to language acquisition, confirming their role in speech impairment and highlighting a significant diagnostic yield among affected Italian patients.
Sex/gender (S/G) differences in ASD language profiles have been poorly investigated. The present study aims to explore whether male (M) and female (F) children with ASD and with normal non-verbal cognitive abilities differ in their linguistic profiles. A sample of 76 Italian children with ASD (range: 4.
View Article and Find Full Text PDFChildhood apraxia of speech (CAS) is a pediatric motor speech disorder. The genetic etiology of this complex neurological condition is not yet well understood, although some genes have been linked to it. We describe the case of a boy with a severe and persistent motor speech disorder, consistent with CAS, and a coexisting language impairment.
View Article and Find Full Text PDFSpecific Learning Disabilities (SLD) are often associated with emotional-behavioral problems. Many studies highlighted a greater psychopathological risk in SLD, describing both internalizing and externalizing problems. The aims of this study were to investigate the emotional-behavioral phenotype through the Child Behavior Checklist (CBCL), and evaluate the mediating role of background and cognitive characteristics on the relationship between CBCL profile and learning impairment in children and adolescents with SLD.
View Article and Find Full Text PDFChildhood apraxia of speech (CAS) is a subtype of motor speech disorder usually co-occurring with language impairment. A supramodal processing difficulty, involving executive functions (EFs), might contribute to the cognitive endophenotypes and behavioral manifestations. The present study aimed to profile the EFs in CAS, investigating the relationship between EFs, speech and language severity, and the connectivity of the frontal aslant tract (FAT), a white matter tract involved in both speech and EFs.
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