Publications by authors named "A M COLAS"
Background: Electronic surveillance systems (ESSs) may assist infection prevention and control (IPC) teams in detecting and monitoring patients infected or colonised by pathogens to prevent healthcare-associated infections. We aimed to assess the impact of implementing an ESS on compliance with isolation precaution measures for bacterial infections or colonizations.
Methods: A quasi-experimental before-after study was conducted using interrupted time series analysis from 1 March 2018 to 31 July 2024 at the University Hospital of Nancy (France).
Skeletal muscle tissue self-repair occurs through the finely timed activation of resident muscle stem cells (MuSC). Following perturbation, MuSC exit quiescence, undergo myogenic commitment, and differentiate to regenerate the injured muscle. This process is coordinated by signals present in the tissue microenvironment, however the precise mechanisms by which the microenvironment regulates MuSC activation are still poorly understood.
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- Respiratory syncytial virus (RSV) causes bronchiolitis in infants, and the monoclonal antibody nirsevimab was approved in the EU in 2022, leading to a national immunisation campaign in France starting September 2023.
- A study was conducted in Paris to evaluate nirsevimab's effectiveness in reducing emergency department visits and hospitalisations for bronchiolitis among infants aged 12 months or younger during the RSV season of 2023-24.
- Out of 2786 infants studied, those who received nirsevimab showed lower rates of emergency visits and hospitalisation for bronchiolitis compared to non-vaccinated infants, but data showed that the majority of those
CREB-regulated transcription co-activator (CRTC) is activated by Calcineurin (CaN) to regulate gluconeogenic genes. CaN also has roles in cardiac hypertrophy. Here, we explore a cardiac-autonomous role for CRTC in cardiac hypertrophy.
View Article and Find Full Text PDFAcetabular dysplasia is a hip condition characterized by abnormal development of the acetabulum, which can be present from birth or develop during childhood and may persist into adulthood. Mild or borderline acetabular dysplasia frequently is associated with cam-type femoroacetabular impingement in adults. Over time, the association of impingement and abnormal contact can lead to hip pain, cartilage damage, labral tears, and an increased risk of developing hip osteoarthritis.
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