Publications by authors named "A M Butts"

The genes - which include and ( ) - evolved from Ty3 retrotransposons and encode proteins that form virus-like capsids. These capsids enable a novel form of intercellular communication by transferring RNAs between cells. However, the specific neuronal circuits and brain processes Arc intercellular signaling regulates remain unknown.

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: While previous survey research has focused on various training constituencies such as trainees, and postdoctoral/internship supervisors, no previous survey research has examined the needs and perspectives of practicum level supervisors and training programs. This study was designed to address this limitation. These results were used in forming the North American Association of Practicum Sites in Neuropsychology (NAPSN).

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New drugs and mechanisms of action targeting are urgently needed to solve the global pandemic of tuberculosis. We previously demonstrated that the 8-hydroxyquinoline series has rapid bactericidal activity against . In this work, we determined that the activity of the 8HQ series is potentiated by copper ions and that the activity is dependent on copper since activity was reduced when copper was depleted from the medium.

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Article Synopsis
  • - We synthesized a new arylsulfonamide that showed effectiveness against both extracellular and intracellular bacilli, while also displaying selectivity in its action against HepG2 cells.
  • - The drug disrupts bacterial cell wall synthesis, likely targeting the MmpL3 protein, which is known to export mycolic acids necessary for the bacterial cell wall.
  • - A specific mutation in the MmpL3 protein led to some resistance against the drug, further supporting the idea that MmpL3 is the main target of the compound's action.
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Introduction: The treatment of cancer is associated with high risk for toxicity and high cost. Strategies to enhance the value, quality, and safety of cancer care are often managed independently of one another. Oncology stewardship is a potential framework to unify these efforts and enhance outcomes.

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