Publications by authors named "A M Brickman"
Introduction: We investigated whether early life exposure to state-level structural sexism influenced late-life memory trajectories among United Staes (U.S.) -born women and men and determined whether associations differed between racialized groups.
View Article and Find Full Text PDFIntroduction: Adults with Down syndrome demonstrate striatum-first amyloid accumulation with [C]PiB PET imaging, which has not been replicated with [F]florbetapir (FBP). Early striatal accumulation has not been temporally quantified with respect to global cortical measures.
Methods: Longitudinal PiB (n=175 participants) and FBP (n=92 participants) data from the Alzheimer Biomarkers Consortium-Down Syndrome were used to measure cortical and striatal binding.
Background: Individuals with adverse pregnancy outcomes have an increased risk of cerebrovascular disease, but the association between adverse pregnancy outcomes and cognitive impairment and dementia is less well established. We aimed to synthesise, combine, and assess the growing body of data examining the associations between adverse pregnancy outcomes and mild cognitive impairment and dementia in parous women.
Methods: In this systematic review and meta-analysis, we searched PubMed (MEDLINE), Web of Science, and Embase from database inception up to July 18, 2024, with no language restrictions, for observational studies or clinical trials that reported mild cognitive impairment or dementia as outcomes and included female individuals or women who had an adverse pregnancy outcome, including hypertensive disorders of pregnancy, gestational diabetes, stillbirth, fetal growth restriction, preterm birth, or placental abruption.
Article Synopsis
- In Ontario, Symptom Response Kits (SRKs) are prescribed for patients with advanced life-limiting illnesses to effectively manage distressing symptoms at the end of life, but there is a concern about the lack of standard procedures for their return and disposal.
- A comprehensive literature review identified 26 studies, mostly from the U.S. and Canada, highlighting the benefits of SRKs while showing a gap in research focusing on the safety and disposal of unused kits.
- The review noted a lack of consistent terminology across studies and OHAH websites, indicating a need for future regulations and standardized practices regarding the safe management of SRKs in the community.
Purpose: The National Institute of Health Toolbox Cognition Battery (NIHTB-CB) is increasingly used in Alzheimer disease (AD) research. We examined the relation of AD biomarkers with performance in the NIHTB-CB in late middle age.
Methods: This is a cross-sectional analysis of 334 Hispanic participants aged 64.