Publications by authors named "A M Boularan"
Article Synopsis
- * Researchers investigated six patients with these mutations, noting symptoms like global motor retardation and recurrent hyperkinetic episodes, with five undergoing deep brain stimulation (GPi-DBS) treatment.
- * Results showed GPi-DBS effectively halted severe hyperkinetic episodes in five patients, highlighting its potential as a life-saving treatment for those with GNAO1 mutations.
Article Synopsis
- Status dystonicus (SD) is a serious and life-threatening condition seen in dystonia patients, with specific demographics and complex characteristics affecting its development.
- A study over 20 years revealed that out of 328 dystonia patients with deep brain stimulation (DBS), 40 developed 58 episodes of SD, mainly with pediatric onset, often accompanied by cognitive impairments and MRI changes.
- The study concluded that while SD can be reversible and results from diverse underlying issues, understanding the complex symptoms, changes, and timelines related to its occurrence is crucial for better management and treatment.
There is currently no consensus for the quantification and identification of weak gammaglobulin monoclonal spike. We conducted a study of 12 months including 410 serum protein electrophoresis (SPE) with suspected weak monoclonal spike in gammaglobulin area without anteriority, which led to the realization of an immunofixation (IF); 276 SPE has a weak spike in gammaglobulins (defined with perpendicular drop method (orthogonal (O) quantification <5 g/L) but only 157 (57%) has monoclonal immunoglobulin by immunofixation of serum. The monitoring of 50 true positive monoclonal immunoglobulins showed the stability of the spike at more than half of the patients and its disappearance in 28% of cases.
View Article and Find Full Text PDF[Setting up of 15 POC blood gas analyzers at Montpellier Hosptital (France)].
Ann Biol Clin (Paris)
December 2016
The purpose of this article is to describe the setting up of 15 blood gas analyzers GEM(®) Premier™ 4000 (IL) at Montpellier hospital. This experience includes analytical characterization (within and between run coefficient of variation) using GSE and GHE IL controls, correlation of 35 samples with a routinely used laboratory blood gas analyzer (Cobas b221, Roche(®)). We shall also develop the training, the habilitation and its follow-up for the user staff (450 people) of the different hospital's units in the aim of the accreditation.
View Article and Find Full Text PDFWe report the case of a man with a massive pulmonary embolism, which lead to cardiac arrest. After ruptured aneurysm clipping, he was successfully treated by rescue thrombolysis administered as compassionate treatment despite the risk of cerebral bleeding. The patient was discharged from the intensive care unit; his initial neurological, cardiac, and pulmonary conditions restored.
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