Publications by authors named "A M Borbat"
Article Synopsis
- A retrospective study evaluated a deep learning AI tool for detecting prostate cancer and grading its severity in biopsy samples, aiming to streamline the time-consuming process of analyzing prostate biopsies.
- The study involved analyzing 5 external patient cohorts, using a total of 5922 tissue sections, and demonstrated the AI's ability to accurately detect tumor presence that some pathologists missed, achieving high sensitivity and specificity scores.
- The AI tool showed comparable accuracy to experienced pathologists in Gleason grading, indicating its potential as a reliable assistant in prostate cancer diagnosis and assessment.
Objectives: Health care systems worldwide are facing a shortage in the pathology workforce that could negatively affect health care services, particularly oncology. To address this potential shortfall, the pathology community must identify the reasons why graduating students are not choosing pathology as a specialty.
Methods: We analyzed 226 free-text essay responses submitted by nonpathology residents at a teaching hospital.
Primary splenic angiosarcoma is a rare and high-grade vascular tumor having a significant metastatic potential. The authors give the data available in the literature and describe their own case of primary splenic angiosarcoma in a 42-year-old male patient with multiple distant metastases in the lymph nodes and skin. The paper shows some difficulties in the morphologic diagnosis of this tumor.
View Article and Find Full Text PDFThe protocol for histological examination of liver transplant dysfunction, which is used at the A.I. Burnazyan, Federal Medical and Biophysical Center and has been developed on the basis of the liver transplant rejection protocol designed at the University of Pittsburgh, is proposed for routine use.
View Article and Find Full Text PDFObjective: To determine the morphological features of IgG4-related lesions and to improve pathomorphological criteria for diagnosing various clinical variants of IgG4-related disease.
Material And Methods: Biopsy and surgical materials from 100 patients with tumor-like lesions at various sites (63 cases of IgG4-related lesion and 37 cases of non-IgG4-related inflammatory processes) were studied. Histological and immunohistochemical studies were conducted to determine the absolute counts of CD138+ cells, IgG+ and IgG4+ in the inflammatory infiltrates, as well as IgG4/IgG and IgG4/CD138 cell ratios.