Publications by authors named "A M Bertoli"
Objectives: The aims of this study were to describe the frequency of pleuropulmonary computed tomography (CT) findings in patients with IgG4-related disease (IgG4-RD) and to compare clinical and laboratory characteristics between patients with and without pleuropulmonary involvement in chest CT.
Methods: This is a study conducted within the IgG4-RD study group of the Argentine Society of Rheumatology (GESAR IgG4) cohort of patients with IgG4-RD. Member centers of the group were requested to submit pulmonary CT scans of the patients.
Context: Rare earth elements (REE) are indispensable in numerous green technologies owing to their exceptional physical and chemical attributes. Separating REE is a pivotal process to meet the increasing demands of the high-tech industry. Understanding the hydrolysis of REE in aqueous environments marks the initial stride in comprehending their separation mechanisms.
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- Next-generation sequencing (NGS) is replacing Sanger sequencing for HIV genotypic drug resistance testing, and this study assessed how consistent different interpretation tools are in a real-world setting.
- The research involved analyzing NGS results from 11 Italian labs using the AD4SEQ HIV-1 Solution v2 kit and compared interpretations from SmartVir, HyDRA Web, and Stanford HIVdb.
- Findings indicated that viremia levels and HIV subtypes influence the validity of NGS-GRT, with only mutations present at frequencies over 10% showing reliable agreement among the interpretation tools.
Article Synopsis
- The study analyzed HIV-1 sequences from 2386 drug-naïve individuals in Italy from 2015 to 2021 to assess the prevalence of transmitted drug resistance (TDR) among them.
- TDR prevalence was found to be 8%, with a slight difference between B subtypes (9.5%) and non-B subtypes (6.1%), and it remained stable over the years assessed.
- The research indicated that certain subtypes were associated with lower TDR rates, emphasizing the need for ongoing monitoring of TDR in newly diagnosed HIV patients to improve treatment strategies.
The Burden of Hereditary Angioedema in a Large Family in Brazil.
Int Arch Allergy Immunol
December 2024
Introduction: Hereditary angioedema (HAE) is a rare genetic disease characterized by submucosal and subcutaneous edema with high morbidity and possibility of mortality. This study presents the sociodemographic characteristics of a large Brazilian family with HAE.
Methods: Descriptive cross-sectional study with patients from two family branches coming from the same city and HAE diagnosis was carried out.