Publications by authors named "A M Benito"
Hypertrophic osteoarthropathy (HOA: MIM 167100)) is classified into primary and secondary types. Primary HOA, also known as pachydermoperiostosis (PDP), is a rare genetic condition with distinct clinical features including digital clubbing, skin thickening, and periostosis. Secondary HOA often occurs as a paraneoplastic syndrome or is associated with systemic diseases.
View Article and Find Full Text PDFArticle Synopsis
- Onchocerciasis and lymphatic filariasis (LF) are diseases prevalent in Equatorial Guinea, with efforts historically focused on Bioko Island, which has successfully interrupted onchocerciasis transmission, prompting a need to assess mainland regions where transmission status is unclear.
- The study, conducted from September to December 2019, employed various diagnostic methods on a sample of 3,951 individuals to estimate the prevalence of these diseases on the mainland, marking the first cross-sectional analysis for this area.
- Results showed a very low onchocerciasis seroprevalence of 0.3%, and while no O. volvulus microfilariae were found in biopsies, DNA evidence confirmed its presence in one
Impact of Genetic and Environmental Factors on Peripheral Refraction.
Transl Vis Sci Technol
October 2024
Article Synopsis
- The study investigates how genetics and the environment affect refractive errors in both monozygotic (MZ) and dizygotic (DZ) twins by examining multiple eye measurements.
- The results show that MZ twins exhibit higher genetic influence in refractive errors compared to DZ twins, particularly for midperipheral defocus, indicating a significant role of genetics in peripheral vision.
- The findings suggest that while environmental factors influence central vision, genetic components play a bigger role in peripheral vision, highlighting the need for tailored approaches in managing conditions like myopia.
Article Synopsis
- The study investigated the reliability of pathologists in quantifying tumor percentages in whole slide images (WSI) of non-small cell lung cancer (NSCLC) using digital image analysis after training them with QuPath.
- Initial assessments showed poor reliability among pathologists, with a low intraclass correlation coefficient (ICC) of 0.09, which only slightly improved to an ICC of 0.24 in a follow-up trial after receiving feedback.
- The research indicated that errors were mainly due to subjective tasks like annotation, and suggested that future AI technologies could enhance accuracy in digital pathology assessments.