Molecular identification of species and biovars associated with animal and human infection in Iran.

Brucellosis is a costly contagious disease of human, domestic and wild animals. It is a serious health problem in Iran causing significant economic losses therefore, control approaches to prevent its spread are of great importance. In Iran, the species and biovars of virulent species are still under-reported due to the inadequate diagnostic protocols and insufficient laboratory facilities.

Cloning and Expression of Gene in as a Food Grade Vaccine.

Background: Brucellosis is still an important health problem in under developing countries and researches for finding efficient vaccine are going on. gene is a good candidate for brucellosis vaccine and investigations showed that ( with several positive characteristic are attractive for protein expression as a live delivery vectors. These fast growing bacteria need no aeration, are easy to handle, have no exotoxin, endotoxin and protease, so the cost of culturing is inexpensive.

A Case of Identity Confirmation of Brucella abortus S99 by Phage Typing and PCR Methods.

Brucellosis is a zoonotic infection that is associated with fever in humans and abortion in animals. The agent of this disease is a facultative intracellular gram-negative coccobacillus called Brucella. There are six classic species, including B.

Genetic characterization of the wboA gene from the predominant biovars of Brucella isolates in Iran.

Introduction: Brucella spp. are gram-negative, facultative intracellular bacteria pathogens responsible for brucellosis, a zoonotic disease that can cause abortion, fetal death, and genital infections in animals and undulant fever in humans. Lipopolysaccharide (LPS) is known as a major virulence factor of Brucella spp.