Background: Hospital-acquired pressure injuries (HAPIs) result in patient harm, discomfort, and even death, with an estimated 2.5 million HAPIs occurring annually in the United States. These pressure injuries from prolonged pressure on the skin and deeper tissues cause reduced blood flow and the breakdown of skin and tissues, resulting in wounds.
View Article and Find Full Text PDFIntroduction: In this article, we offer an overview of the Capdroits participatory research approach, initially focusing on the controversy surrounding Article 12 of the International Convention of Persons with Disabilities, “Recognition of legal personality under conditions of equality.” Its objective is to encourage the participation of the people concerned by Article 12. It brings together academic researchers, experts in support relationships, and people directly concerned by impediment situations.
View Article and Find Full Text PDFThe discovery of gasdermin D (GSDMD) as the terminal executioner of pyroptosis provided a large piece of the cell death puzzle, whilst simultaneously and firmly putting the gasdermin family into the limelight. In its purest form, GSDMD provides a connection between the innate alarm systems to an explosive, inflammatory form of cell death to jolt the local environment into immunological action. However, the gasdermin field has moved rapidly and significantly since the original seminal work and novel functions and mechanisms have been recently uncovered, particularly in response to infection.
View Article and Find Full Text PDFAdaptive oscillators are a subset of nonlinear oscillators that can learn and encode information in dynamic states. By appending additional states onto a classical Hopf oscillator, a four-state adaptive oscillator is created that can learn both the frequency and amplitude of an external forcing frequency. Analog circuit implementations of nonlinear differential systems are usually achieved by using operational amplifier-based integrator networks, in which redesign procedures of the system topology is time consuming.
View Article and Find Full Text PDFAtmospheric pollutant data retrieved through satellite sensors are continually used to assess changes in air quality in the lower atmosphere. During the COVID-19 pandemic, several studies started to use satellite measurements to evaluate changes in air quality in many different regions worldwide. However, although satellite data is continuously validated, it is known that its accuracy may vary between monitored areas, requiring regionalized quality assessments.
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