Publications by authors named "A M Bartholomew"
Article Synopsis
- The study investigates the effects of prolonged ischaemia during partial nephrectomy (PN) on kidney function, highlighting a lack of research in this area despite its clinical importance.
- Among 1371 patients, the analysis focused on 759 who had assessments on kidney function pre- and post-surgery, looking at recovery rates related to ischaemia type and duration.
- Findings revealed that while warm ischaemia showed a significant negative impact on kidney recovery after 30 minutes, cold ischaemia maintained higher recovery rates, suggesting the need to limit warm ischaemia duration for better patient outcomes.
Context: Osteoporosis is a prevalent concern, particularly among aging populations, leading to increased risk of fractures, including those related to hip and knee arthroplasty procedures. Screening for osteoporosis, especially with dual X-ray absorptiometry (DXA) scans, is crucial for early detection and management.
Objectives: This study aimed to assess adherence to osteoporosis screening guidelines among patients aged 65 and older undergoing elective total hip arthroplasty (THA) or total knee arthroplasty (TKA) within a single health network.
Anomalous X-ray diffraction (AXD) and neutron diffraction can be used to crystallographically distinguish between metals of similar electron density. Despite the use of AXD for structural characterization in mixed metal clusters, there are no benchmark studies evaluating the accuracy of AXD toward assessing elemental occupancy in molecules with comparisons with what is determined via neutron diffraction. We collected resonant diffraction data on several homo and heterometallic clusters and refined their anomalous scattering components to determine metal site occupancies.
View Article and Find Full Text PDFIntroduction: Development of technical skills is a vital component of surgical residency. The use of animal tissues for operative simulation leads to both the loss of animal life and financial costs for the institution. We hypothesized that maximizing tissue use from investigational large animal models after euthanasia could reduce loss of animal life and institutional costs by replacing commercially purchased tissues.
View Article and Find Full Text PDFArticle Synopsis
- Gestational diabetes mellitus (GDM) is a common pregnancy complication, requiring glycaemic control to prevent negative outcomes for both the mother and baby, with about 25% needing medication like insulin or metformin.
- A study will compare the effectiveness and safety of metformin versus insulin in a diverse group of 1572 pregnant individuals needing treatment, tracking their health and their children's health for two years.
- Ethical approval has been obtained, and plans include publishing detailed results on the findings related to treatment experiences and safety outcomes.