Publications by authors named "A M Babs'kyĭ"

A comparative analysis of the content and the list of codified occupations (CO) of State classifiers (SC) of occupations SC 003-95 and SC 003:2010 (total 15 000 positions) is considered. Found that the number of corresponding CO in the SC 003-95 consist of 906 items including 57 of Vol. 78 "Care of public health", as well as in SC 003:2010 - 799 and 59 respectively.

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Using diffusion weighted 1H, single-quantum 23Na and triple-quantum-filtered 23Na magnetic resonance imaging water apparent diffusion coefficient (ADC), total tissue Na+ and intracellular Na+ were monitored in hepatocellular carcinoma (HCC) in rats and in the surrounding liver tissue. The tumor water ADC was approximately 50% higher compared to the nearby healthy liver tissue but did not increase during 28 days of tumor growth (double time 3.9 days).

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The direct measurement of temperature in subcutaneously (sc) implanted tumors shows that the actual tumor temperature is by 3-4 degrees C lower than the normal body temperature. Thus, the temperatures usually used for tumor hyperthermia are in fact heating the sc-tumors from 33 to 37 degrees C. The temperature increase during the perfusion of radiation-induced fibrosarcoma (RIF-1) cells from 33 to 37 degrees C caused a reversible increase in intracellular 23Na ([Na+]i) NMR signal intensity by 50-60%.

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A sublethal dose of sodium nitrates (60 mg/kg) 30 min after intraperitoneal administration to rats increases ADP-stimulated respiration, when succinate is used as the substrate. Its stimulating action is associated with an increase of efficiency of oxygen utilization. Intraperitoneal administration of succinic acid in a dose of 25 mg/kg normalizes changes induced by nitrites.

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Nitrite incubation in mitochondria and nitrate intoxication of rats have been studied for their effect on aerobic energetic processes in the liver. Sodium nitrite in concentration of 2 mg/l causes an inhibition of ADP-stimulated respiration and provides uncoupling processes of oxidative phosphorylation and respiration in mitochondria, when adding succinate as a substrate. Low doses of nitrate in vivo promote oxygen economization in mitochondria.

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