Unlocking a Decade of Research on Embryo-Derived Extracellular Vesicles: Discoveries Made and Paths Ahead.

Over the past decade, research on embryo-derived extracellular vesicles (EVs) has unveiled their critical roles in embryonic development and intercellular communication. EVs secreted by embryos are nanoscale lipid bilayer vesicles that carry bioactive cargo, including proteins, lipids, RNAs, and DNAs, reflecting the physiological state of the source cells. These vesicles facilitate paracrine and autocrine signaling, influencing key processes such as cell differentiation, embryo viability, and endometrial receptivity.

The outcome of functional constipation in Saudi children.

Background: Understanding the outcome of functional constipation (FC) for both patients and physicians is essential, yet it has been infrequently reported worldwide. The objective of this report was to update the outcomes of FC in Saudi children.

Methods: Clinical data including age, sex, response to management, duration of follow up, and type of management were collected from the notes of each clinic visits and phone call follow-ups.

Bibliometric analysis: A few suggestions (Part Two).

This manuscript serves as a follow-up to our previous work, "bibliometric analysis: a few suggestions," where we highlighted key aspects of bibliometric research and offered recommendations for improving its rigor. In this draft, we expand on those ideas and provide additional suggestions aimed at enhancing the depth and scope of bibliometric analysis. By analyzing a few randomly selected bibliometric studies, we identified common practices and gaps in the field, which informed the inclusion of new recommendations not covered in our earlier paper.

Status of Inappropriate Complementary Feeding and Its Associated Factors Among Infants of 9-23 Months.

Inappropriate complementary feeding during the first two years of life significantly impacts children's health, increasing risks of malnutrition and illness. : This study investigates factors influencing early feeding patterns among 600 mothers of children aged 9-23 months in selected hospitals in Punjab, Pakistan. Using a structured questionnaire, data were collected and analyzed, with associations measured by odds ratios (ORs) and 95% confidence intervals (CIs).