Publications by authors named "A M Aponte"
COVID-19 Impact On Black and Latina Women: Pregnancy and Parenting.
J Racial Ethn Health Disparities
January 2025
The coronavirus-19 (COVID-19) pandemic presented unique challenges for pregnant women and birthing individuals, particularly those from Black and Latino communities. Understanding the impact of the pandemic on their experiences is crucial for providing adequate support and care during vulnerable times. This research delves into the specific effects of COVID-19 on maternal stress and resilience.
View Article and Find Full Text PDFColorectal cancer (CRC) is a multifactorial disease driven by genetic and epigenetic alterations that modulate specific metabolic pathways. Despite the availability of effective treatments like 5-fluorouracil (5-FU), pharmacological therapy for CRC still faces significant challenges, including drug resistance, toxicity, and limited specificity. Therefore, discovering new compounds remains critical to overcoming these barriers and expanding treatment options.
View Article and Find Full Text PDFNew complex cell junctions in and around the intervertebral discs discovered using autoantibodies from patients affected by endemic pemphigus foliaceus in El Bagre, Colombia, South America.
Int J Dermatol
September 2024
Article Synopsis
- The study investigates a new variant of endemic pemphigus foliaceus in El Bagre, Colombia, which causes back pain in patients and focuses on the reactivity of their autoantibodies to intervertebral disks (IVDs).
- Researchers used various diagnostic methods, including questionnaires and advanced microscopy, to analyze patient sera and compare them with control sera from healthy individuals in the area.
- Results showed that patients' sera contained antibodies targeting newly identified cell junctions in the IVDs and surrounding structures, suggesting a deeper understanding of spinal diseases and potential implications for treatment.
Orbital and ocular adnexal lymphoma (OAL) affects the orbit and the surrounding structures and can arise as several subtypes with variable prognoses. We performed an observational study on the relationship between OAL subtype, diagnostic features, and prognosis to offer valuable insights into imaging techniques, such as Positron Emission Tomography with 2-deoxy-2-[fluorine-18] fluoro-D-glucose integrated with Computed Tomography (F-FDG PET-CT), in predicting outcomes. With this aim, we retrospectively reviewed 99 patients with OALs, recording demographics, cancer subtype, location and treatment, FDG avidity, and bone marrow positivity.
View Article and Find Full Text PDFBackground: Oxidized apolipoprotein B (oxLDL) and oxidized ApoA-I (oxHDL) are proatherogenic. Their prognostic value for assessing high-risk plaques by coronary computed tomography angiography (CCTA) is missing.
Methods: In a prospective, observational study, 306 participants with cardiovascular disease (CVD) had extensive lipoprotein profiling.