Publications by authors named "A M Abu Bakar"
The effect of open-pit bauxite mining on beach sediment contamination in the urban coastal environment of Kuantan City, Malaysia, was investigated. The contents of 11 heavy metals (Pb, Cd, Al, Mn, Cu, Zn, Fe, As, Ni, Cr, and Ag) in 30 samples from Kuantan beach sediment zones (supratidal, intertidal, and subtidal) were determined using inductively coupled plasma optical emission spectrometry followed by contamination indexes, Pearson's correlation analysis, and principal component analysis (PCA). The results indicated that Cd, As, Ni, and Ag values in beach sediment zones were significantly higher compared to background values.
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- The study examined thyroid cancer cases at a hospital in Najran, Saudi Arabia, involving 279 patients from 2014 to 2021, primarily affecting women with a mean age of 42.8 years.
- Most patients (60.9%) underwent total thyroidectomy, with a significant number showing localized disease; papillary and follicular cancers were the most common types.
- Independent factors influencing mortality included older age, diabetes, certain cancer subtypes, and metastatic disease, with particularly high risks associated with tumor size and pulmonary metastasis.
Type-two diabetes, characterised by insulin resistance or inadequate insulin production, is prevalent among adults. The α-amylase enzyme contributes to carbohydrate digestion, elevating postprandial glucose levels. Natural compounds like caffeic acid offer a solution.
View Article and Find Full Text PDFThis study aimed to determine the expression pattern of autoantibody proteins from the serum of grade IV glioblastoma patients. We performed high throughput antibody profiling via the Sengenics i-Ome Protein Array to determine the differentially expressed autoantibodies. The results portrayed that anti-COL4A3BP and anti-HSP90AA1 were among the upregulated autoantibodies in glioblastoma sera.
View Article and Find Full Text PDFBackground: Despite advances in treatment, pancreatic cancer frequently has a low survival rate due to its advanced-stage diagnosis. Treatment focuses on prolonging survival and maintaining quality of life. This study investigates the characteristics associated with survival in advanced pancreatic cancer patients treated at a single academic cancer center in Najran, Saudi Arabia.
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