Publications by authors named "A M Aboul-Naga"
Background: DNA methylation is an epigenetic mechanism that takes place at gene promoters and a potent epigenetic marker to regulate gene expression.
Objective: The study aimed to improve the milk production of Zaraibi goats by addressing the methylation pattern of two milk production-related genes: the growth hormone receptor (GHR) and the growth differentiation factor-9 (GDF-9).
Methods: 54 and 46 samples of low and high milk yield groups, respectively, were collected.
Article Synopsis
- This study aimed to explore the genomic traits of local Egyptian goat breeds, focusing on Nubian, Damascus, Barki, and Boer goats, identifying selection signatures, homozygosity runs, and inbreeding coefficients (F).
- A total of 46,268 SNP markers were analyzed across 337 goats, revealing an average of 145.44 ROHs in Nubian goats, while the highest inbreeding coefficient was found in Nubians (~0.12) and the lowest in Barki (~0.03).
- Significant genes linked to immunity, reproduction, embryonic development, and adaptation to the local environment were found in the genomic regions, providing insights for better breeding and conservation
Heat stress caused by climatic changes is one of the most significant stresses on livestock in hot and dry areas. It has particularly adverse effects on the ability of the breed to maintain homeothermy. Developing countries are advised to protect and prepare their animal resources in the face of potential threats such as climate change.
View Article and Find Full Text PDFCisplatin exposure represents a significant fertility problem for childhood cancer. In this study we examined the possible therapeutic role of Zinc oxide nanoparticles (ZnO-NPs) on Cisplatin (Cis) induced impairment in the spermatogenesis initiation during puberty. Seventy-two male rats aged 30 days were distributed into four equal groups: Control group; ZnO-NPs group (intraperitoneal i.
View Article and Find Full Text PDFAims: As the spermatogenesis process is targeted by cisplatin (Cis) that changes testicular morphology, alters sperm quality, and hence causes male infertility. This study investigated the possible therapeutic effects of l-carnitine (LC) on Cis impaired spermatogenesis's establishment during the prepubertal phase.
Materials And Methods: Ninety-six prepubertal Sprague Dawley male rats were divided into four groups.