Publications by authors named "A M A Badreldin"
This study examined the molecular phenotypes of adipose-derived stem cells (ASCs) and vaginal fibroblasts (VFBs) and assessed whether pelvic organ prolapse (POP) affects their biological properties. We performed RNA sequencing of paired ASCs and VFBs from six patients with POP and six controls (CTRL). The transcriptomes of POP and CTRL in either ASCs or VFBs were compared (DESeq2, false discovery rate (FDR) < 0.
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- Radical prostatectomy (RP) is a key surgical treatment for prostate cancer, but assessing surgical margins during the procedure is difficult and costly, making fluorescence confocal microscopy (FCM) a potential solution.
- The IP8-FLUORESCE study is a multicentre, prospective study that investigates the accuracy of digital FCM in identifying prostate cancer at surgical margins, comparing it to traditional histopathology methods.
- The study will involve 153 patients undergoing robot-assisted RP, using FCM on prostate specimens immediately after surgery, with results evaluated by blinded uro-pathologists for accuracy in detecting cancer presence at the margins.
Regenerative dental medicine continuously expands to improve treatments for prevalent clinical problems in dental and oral medicine. Stem cell based translational opportunities include regenerative therapies for tooth restoration, root canal therapy, and inflammatory processes (e.g.
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