Publications by authors named "A Luzurier"

Purpose: The purpose of this study was to investigate the relationship between inter-reader variability in manual prostate contour segmentation on magnetic resonance imaging (MRI) examinations and determine the optimal number of readers required to establish a reliable reference standard.

Materials And Methods: Seven radiologists with various experiences independently performed manual segmentation of the prostate contour (whole-gland [WG] and transition zone [TZ]) on 40 prostate MRI examinations obtained in 40 patients. Inter-reader variability in prostate contour delineations was estimated using standard metrics (Dice similarity coefficient [DSC], Hausdorff distance and volume-based metrics).

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Article Synopsis
  • The study compared the accuracy of different methods for estimating prostate volume (PV) in MRI scans for cancer management, focusing on manual planimetry (MPM), traditional ellipsoid formula (TEF), and biproximate ellipsoid formula (BPEF).
  • Both TEF and BPEF overestimated PV compared to MPM, which was found to have extremely high reliability and the lowest variability among the methods.
  • This research highlights MPM as the most reliable technique for PV estimation, crucial for decisions based on prostate-specific antigen density, which can impact patient treatment plans.
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Article Synopsis
  • Accurate prostate zonal segmentation is essential for automated prostate cancer detection, and this study assesses manual segmentation variability among radiologists using T2-weighted MRI images.
  • Seven radiologists evaluated 40 prostate MRI images, analyzing factors like anatomical variations and imaging techniques, with metrics like Dice Score to quantify differences.
  • Results show that segmentation variability is higher at the apex and base of the prostate and influenced by morphological changes, with the radiologist's experience having a minimal effect on variability.
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Background: The incremental value of dynamic contrast-enhanced (DCE) imaging in localizing radiorecurrent prostate cancer is uncertain.

Purpose: To assess the added-value of DCE imaging to the combination T -weighted imaging (T W)+diffusion-weighted imaging (DWI) in detecting locally radiorecurrent prostate cancer (PCa), by radiologists with different levels of experience.

Study Type: Analytic retrospective study.

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