[Immunopathological studies of the skin of patients with pemphigoid at different stages of the disease].

The aim of the investigation was to demonstrate whether there is a correlation, in patients with bullous pemphigoid (BP), between the presence of immune deposits in the skin and the activity of the pathological process. We investigated 39 cases with a BP anamnese dating from 3 months up to 17 years. We repeated the investigations several times by means of direct immunofluorescence method in different disease activity.

[Clinical usefulness of determining the antibodies to soluble nuclear antigens in various collagen diseases].

The purpose of the study was evaluation of the clinical usefulness of determination of antibodies to soluble nuclear antigens. The study was carried out in 71 cases of various collagen diseases. Antibodies dsDNA (IIF method with Crithidium luciliae as substrate) were found only in patients with SLE and renal involvement.