Publications by authors named "A Lugo"
Introduction: Relative or absolute safety of heated tobacco products (HTP) remains unknown, while independent literature suggests that these products do not favour tobacco control. We conducted a comprehensive systematic review and meta-analysis to evaluate HTP usage patterns and the effect of HTP use on conventional tobacco smoking (use transitions).
Methods: We used Pubmed/MEDLINE, Embase and the Cochrane Library to identify all articles published up to February 2022 on HTP use.
We describe herein the design and synthesis of a new class of dialkylarylphosphine ligands incorporating a Lewis-basic urea subunit. The ligand synthesis consisted of six linear steps and was enabled by the discovery of a new N-to-N alkyl migration reaction. This new series of dialkylarylphosphine urea ligands were applied in common palladium-catalyzed cross-coupling reactions for the formation of carbon-carbon and carbon-nitrogen bonds in moderate to high yields.
View Article and Find Full Text PDFObjective: Psychoactive substance use is largely found to involve multiple substances. In recent years, the COVID-19 pandemic has changed psychoactive substance use patterns. Aim of this study is to investigate profiles of polysubstance and their pattern during and after the COVID-19 pandemic.
View Article and Find Full Text PDFArticle Synopsis
- The COVID-19 lockdowns significantly altered alcohol consumption habits in Italy, showing a shift from 26.4% at-risk drinkers before the pandemic to around 30% in the years following the initial lockdown.
- A study involving over 6,000 adults utilized an online questionnaire and focused on demographic factors, revealing higher at-risk drinking rates among younger individuals, those experiencing anxiety or depression, and users of nicotine products.
- Ultimately, the findings suggest concern as long-term alcohol consumption trends worsened, highlighting a greater risk among specific populations, including younger adults and married individuals, with mental health issues playing a significant role.
Article Synopsis
- Lung cancer is the leading cause of cancer deaths globally, and this study investigates how second-hand smoke (SHS) affects lung cancer risk in people who never smoked.
- A systematic review and meta-analysis of 126 studies revealed that SHS exposure increases lung cancer risk by 24%, with higher risks found in specific settings like workplaces and homes.
- The findings confirm that longer and more intense exposure to SHS significantly raises the chance of developing lung cancer in never-smokers.