Effectiveness of ceftazidime-avibactam versus ceftolozane-tazobactam for multidrug-resistant Pseudomonas aeruginosa infections in the USA (CACTUS): a multicentre, retrospective, observational study.

Background: Ceftolozane-tazobactam and ceftazidime-avibactam are preferred treatment options for multidrug-resistant Pseudomonas aeruginosa infections; however, real-world comparative effectiveness studies are scarce. Pharmacokinetic and pharmacodynamic differences between the agents might affect clinical response rates. We aimed to compare the effectiveness of ceftolozane-tazobactam and ceftazidime-avibactam for treatment of invasive multidrug-resistant P aeruginosa infections.

Impact of Postnatal Head Circumference Growth in Normocephalic Infants Prenatally exposed to Zika Virus in Puerto Rico.

Objective: We aimed to describe the head circumference (HC) growth trends for non-microcephalic infants exposed to the Zika virus (ZIKV) in utero.

Methods: This was a medical record review of non-microcephalic neonates exposed to ZIKV whose mothers received prenatal care at the fetal evaluation unit (2015-2017). The mean HC values of babies from prenatal age to 1 year old were compared with the standardized values on HC growth charts.

[Qualitative analysis of voluntary abortion in the Hospital Italiano de Buenos Aires].

Introduction: The Voluntary Interruption of Pregnancy (IVE) law 27.610, enacted in 2020, urges healthcare providers to guarantee this practice. Previous investigations at the Hospital Italiano de Buenos Aires (HIBA) revealed that the lack of clear institutional protocols hindered the management of abortion.

Scalable policy adoption and sustainable implementation of surgical care in the Americas.

On September 29, 2023, the Republic of Ecuador convened a meeting to address surgical system strengthening and urge political leaders to invest in surgical infrastructure. The meeting included experts in health diplomacy, innovative financing, implementation strategy and national surgical plans. The event occurred in parallel with the Sixtieth Directing Council of the Pan American Health Organization, Seventy-fifth session of the World Health Organization Regional Committee for the Americas.

MICCAI-CDMRI 2023 QuantConn Challenge Findings on Achieving Robust Quantitative Connectivity through Harmonized Preprocessing of Diffusion MRI.

White matter alterations are increasingly implicated in neurological diseases and their progression. International-scale studies use diffusion-weighted magnetic resonance imaging (DW-MRI) to qualitatively identify changes in white matter microstructure and connectivity. Yet, quantitative analysis of DW-MRI data is hindered by inconsistencies stemming from varying acquisition protocols.