Palliative care management of head and neck cancer patients amongst oral and maxillofacial surgeons: A novel national survey assessing knowledge, decision making, perceived confidence, and training in the UK.

Palliative care strives to improve the quality of life of patients experiencing life-limiting conditions by providing personalised holistic care. Head and neck cancer patients may require palliation at different stages of their disease, thus timely recognition and management is vital when considering supportive care. This study assesses the awareness, perceived confidence, and knowledge of palliative care management of UK-based oral and maxillofacial surgery (OMFS) head and neck surgeons.

Correlation of maximal nasal septal deviation with deviation at the maxillary insertion.

Purpose: It is unclear if septal deviation at the insertion points to the nasal cavity is associated with the overall septal deviation. This study aimed to assess septal deviation at the cribriform plate (CP) and maxillary crest (MC) using CT scans and to see if there was any correlation with overall septal deviation.

Methods: All consecutive CT sinus scans between January 2020 and December 2021 were retrospectively reviewed.

The effect of photobiomodulation on tinnitus: a systematic review.

Objective: To establish outcomes following photobiomodulation therapy for tinnitus in humans and animal studies.

Methods: A systematic review and narrative synthesis was conducted in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses statement. The databases searched were: Medline, Embase, Cochrane Central Register of Controlled Trials ('Central'), ClinicalTrials.

The effect of photobiomodulation on hearing loss: A systematic review.

Objectives: To assess outcomes associated with photobiomodulation therapy (PBMT) for hearing loss in human and animal studies.

Design: Systematic review and narrative synthesis in accordance with PRISMA guidelines.

Setting: Data bases searched: MEDLINE, EMBASE, CENTRAL, ClinicalTrials.

Novel 2-Thiouracil-5-Sulfonamide Derivatives: Design, Synthesis, Molecular Docking, and Biological Evaluation as Antioxidants with 15-LOX Inhibition.

New antioxidant agents are urgently required to combat oxidative stress, which is linked to the emergence of serious diseases. In an effort to discover potent antioxidant agents, a novel series of 2-thiouracil-5-sulfonamides (-) were designed and synthesized. In line with this approach, our target new compounds were prepared from methyl ketone derivative , which was used as a blocking unit for further synthesis of a novel series of chalcone derivatives -, thiosemicarbazone derivatives -, pyridine derivatives - and -, bromo acetyl derivative , and thiazole derivatives -.