Publications by authors named "A Losco"

Article Synopsis
  • The study aimed to determine the prevalence of disease-related malnutrition (DRM) and micronutrient deficiencies in patients with inflammatory bowel disease (IBD), while also identifying related risk factors.
  • Among the 295 IBD patients assessed, 23% were found to have DRM, with no significant difference between those with Crohn's disease and those with ulcerative colitis.
  • Factors such as low body mass index (BMI), recent hospitalizations, and disease activity were linked to DRM, highlighting that malnutrition and micronutrient deficiencies are common in the IBD population and relate to health complications.
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Background And Aims: Perception of quality of care is important in the management of patients with chronic diseases, particularly inflammatory bowel disease.

Aims And Methods: This longitudinal study aimed to investigate variations of the Quality of Care through the Patients' Eyes (QUOTE-IBD) questionnaire scores one year after the basal evaluation in the Studio Osservazionale quaLità cUre malatTIe crOniche intestiNali (SOLUTION-1) study.

Results: Of the cohort of 992 patients, 936 were evaluable.

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Crohn's disease is a chronic inflammatory disease which may involve any segment of the gastrointestinal tract, most frequently the terminal ileum, the large intestine, and the perianal region. The symptoms of perianal Crohn's disease include skin disorders, hemorrhoids, anal ulcers, anorectal stenosis, perianal abscesses and fistulas, rectovaginal fistulas and carcinoma of the perianal region. The perianal manifestations of Crohn's disease cause great discomfort to the patient and are among the most difficult aspects to treat.

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Background: Where population coverage is limited, the exclusive use of Cancer Registries might limit ascertainment of incident cancer cases. We explored the potentials of Nationwide hospital discharge records (NHDRs) to capture incident breast cancer cases in Italy.

Methods: We analyzed NHDRs for mastectomies and quadrantectomies performed between 2001 and 2008.

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Background: Methotrexate is considered a treatment for Crohn's disease, whilst few data in ulcerative colitis are available.

Aim: To evaluate frequency, indications, efficacy and safety of methotrexate in inflammatory bowel disease patients.

Methods: 5420 case histories were reviewed.

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