Publications by authors named "A Lorenzova"
Article Synopsis
- hsCRP (high sensitivity C-reactive protein) is a marker for premature atherosclerosis, with levels over 2 mg/l indicating higher risks for heart attacks and strokes, but its interpretation is complicated by other cardiovascular risk factors.
- A study of the Czech population found that hsCRP correlates with BMI, waist circumference, and triglycerides, with differing trends in men and women—men see a steady increase, while women show an increase only after menopause.
- Weight loss and increased physical activity in young obese women lead to a significant reduction in hsCRP levels, indicating a potential link to genetics and inflammation related to central obesity and triglyceride metabolism.
Background: Apolipoprotein A5 (APOA5) is a determinant of plasma lipids, and its role in body mass index (BMI) determination is discussed. This study was aimed at the investigation of the relationship between common APOA5 gene variants and body weight/plasma lipid decrease in overweight females.
Methods: We analyzed 98 unrelated overweight and obese nondiabetic Czech females (BMI >27.
Background: It has been shown that high-sensitivity C-reactive protein (hsCRP) concentrations are associated with elevated risk of myocardial infarction, but the mechanisms regulating hsCRP concentration are not completely elucidated yet. In our study, association of interleukin-10 (IL-10) and CD14 polymorphisms and environmental factors with the risk of myocardial infarction was studied.
Methods: The study group consisted of 284 male patients aged below 65 years, admitted to hospital for myocardial infarction.