Publications by authors named "A Lopez-Rubio"

The study investigates the composition and properties of unpopped and expanded popcorn, analyzing monosaccharides, protein, amylose, polyphenols, physical traits, crystallinity, and in vitro digestion. Unpopped grains had high glucose content (mainly from starch), which decreased by 20 % in expanded popcorn, especially in black and red A samples. Expanded grains showed higher protein levels (up to 15 %), particularly in red B and yellow samples.

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  • This study explores a circular economy approach using hemp stems and rice straw to create sustainable alternatives for plastic absorbent pads in food packaging.
  • The active material, made from hemp cellulose and a bioactive extract from rice straw, not only reduces plastic waste but also improves food preservation.
  • The developed cryogels demonstrated favorable properties for meat preservation, with a careful balance of bioactive extract concentrations to optimize antioxidant benefits without inducing negative reactions.
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This study presents a novel biotechnological approach for creating water vapor-resistant cryogels with improved integrity. Rice straw cellulose was transformed into nanofibrils through TEMPO-mediated oxidation and high-pressure homogenization. The resulting cryogels remained firm even when immersed in aqueous media, whose pores were used by live cell to deposit polyhydroxyalkanoate (PHA) particles inside them.

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  • Post-transcriptional mechanisms play a vital role in maintaining progenitor cell identity and can be disrupted in cancer, particularly in acute myeloid leukemia (AML).
  • Researchers used CRISPR screens to discover that regulators of P-bodies, which are cellular structures involved in RNA processing, are essential for the development and upkeep of AML.
  • The study shows that while P-body loss minimally affects normal blood cell production, it significantly alters the behavior of leukemia cells by releasing tumor suppressor mRNAs, leading to changes in gene expression and potential new treatment strategies for myeloid leukemia.
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Reprogramming somatic cells into induced pluripotent stem cells (iPSCs) requires activation of the pluripotency network and resetting of the epigenome by erasing the epigenetic memory of the somatic state. In female mouse cells, a critical epigenetic reprogramming step is the reactivation of the inactive X chromosome. Despite its importance, a systematic understanding of the regulatory networks linking pluripotency and X-reactivation is missing.

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