Publications by authors named "A Longoni"
Article Synopsis
- The study aimed to investigate links between serum vitamin D levels and depressive/anxiety symptoms in women during pregnancy and after childbirth, analyzing various qualifying research studies.* -
- A total of 25 studies were included, revealing that lower vitamin D levels were significantly associated with higher rates of depressive symptoms both before and after childbirth, while only one study suggested a potential link with anxiety.* -
- The evidence presented is of low quality, indicating a need for more thorough research, particularly longitudinal studies, to better understand these relationships between vitamin D levels and mental health during and after pregnancy.*
Article Synopsis
- About 6-13% of women globally experience antenatal depression (AD), which can harm both mother and baby; the study explored the link between vitamin D deficiency and AD in pregnant women in Pelotas, Brazil.
- A cross-sectional study analyzed blood samples from 180 pregnant women (50 with depression) to measure levels of 25-hydroxyvitamin D, finding a significant association between vitamin D deficiency and AD.
- The findings suggest that maintaining adequate vitamin D levels during pregnancy may help reduce the risk of AD and support maternal mental health, potentially benefiting child development as well.
Endochondral bone regeneration is a promising approach in regenerative medicine. Callus mimics (CMs) are engineered and remodeled into bone tissue upon implantation. The long-term objective is to fabricate a sustainable off-the-shelf treatment option for patients.
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- Microcarrier expansion systems are promising for scaling up mesenchymal stromal cell (MSC) therapies, making them more economical for clinical use.
- New microcarriers with customizable properties aim to enhance how cells grow, but they still need more biological testing and compatibility checks with dynamic culture setups.
- There has been progress in creating the infrastructure for scaling these technologies, but challenges still exist in understanding how different microcarrier properties affect MSC behavior and function.